Mississippi Meatball Recipe Easy and Delicious Meal Ideas

Updated On: October 14, 2025

If you’re craving a hearty, flavorful dish that combines tender meatballs with a rich, creamy sauce, the Mississippi Meatball recipe is your go-to comfort food. Originating from the southern United States, this recipe has gained popularity for its unique blend of tangy pepperoncini peppers, savory ranch seasoning, and melted cheese, all slow-cooked to perfection.

Whether you’re cooking for a family dinner or preparing a game day feast, Mississippi Meatballs deliver a crowd-pleasing taste that’s both simple and indulgent.

What sets this recipe apart is the effortless slow cooker method that allows the flavors to meld beautifully while you go about your day. Plus, it’s incredibly versatile—serve it over mashed potatoes, rice, or even on a sandwich roll for a delicious meatball sub.

Ready to dive into one of the most satisfying meatball recipes you’ll ever make? Let’s explore why Mississippi Meatballs are a must-try addition to your recipe collection.

Why You’ll Love This Recipe

Mississippi Meatballs are beloved for several reasons. First, they combine classic comfort food elements—juicy meatballs, creamy ranch seasoning, and tangy pepperoncini peppers—that create an unforgettable flavor profile.

The slow cooker approach means minimal prep and maximum taste, making dinner time stress-free and delicious.

Additionally, this recipe is incredibly adaptable. You can customize it with your favorite cheese or add extra spices to suit your palate.

The hearty meatballs are perfect for family meals, potlucks, or even meal prepping. If you love recipes that require little effort but offer big rewards, Mississippi Meatballs will quickly become a staple in your kitchen.

Ingredients

  • 2 lbs ground beef (80/20 for best flavor)
  • 1 cup Italian breadcrumbs
  • 2 large eggs
  • 1/2 cup grated Parmesan cheese
  • 1/4 cup chopped fresh parsley
  • 2 teaspoons garlic powder
  • 1 teaspoon onion powder
  • Salt and black pepper to taste
  • 1 packet (1 oz) ranch seasoning mix
  • 1/2 cup unsalted butter (1 stick)
  • 4-5 pepperoncini peppers, sliced
  • 1 cup shredded mozzarella cheese
  • Optional: 1/2 cup beef broth for extra sauce

Equipment

  • Slow cooker (4 to 6-quart size recommended)
  • Large mixing bowl
  • Baking sheet or plate for shaping meatballs
  • Measuring cups and spoons
  • Mixing spoon or spatula
  • Cheese grater (if grating fresh cheese)
  • Knife and cutting board (for chopping parsley and slicing peppers)

Instructions

  1. Prepare the meatballs: In a large mixing bowl, combine the ground beef, Italian breadcrumbs, eggs, Parmesan cheese, chopped parsley, garlic powder, onion powder, salt, and pepper. Mix gently until all ingredients are incorporated, being careful not to overwork the meat to keep the meatballs tender.
  2. Shape the meatballs: Roll the mixture into 1.5-inch meatballs, placing them on a baking sheet or plate. You should have approximately 24-28 meatballs depending on size.
  3. Layer in the slow cooker: Place the meatballs evenly in the slow cooker. Sprinkle the ranch seasoning mix over the meatballs. Add the sliced pepperoncini peppers on top.
  4. Add butter and optional broth: Cut the butter into slices and place evenly over meatballs. If you prefer a saucier dish, pour in the beef broth around the edges of the slow cooker—this helps distribute flavors without washing out the seasoning.
  5. Cook low and slow: Cover and cook on low for 6-7 hours or on high for 3-4 hours. The meatballs should be cooked through and tender, and the sauce will be bubbling and flavorful.
  6. Finish with cheese: About 15 minutes before serving, sprinkle the shredded mozzarella cheese evenly over the meatballs. Cover and let the cheese melt until bubbly and golden.
  7. Serve and enjoy: Carefully scoop the meatballs and sauce onto plates or over your favorite side dish. Garnish with extra parsley if desired.

Tips & Variations

For a twist on tradition, try swapping the ground beef for ground turkey or chicken for a leaner option. Adding a splash of Worcestershire sauce to the meat mixture adds a deeper umami flavor.

If you want a spicier kick, include some crushed red pepper flakes along with the ranch seasoning. Alternatively, substitute pepperoncini with banana peppers or mild jalapeños depending on your heat preference.

To make this recipe gluten-free, use gluten-free breadcrumbs or crushed pork rinds. Serve over mashed cauliflower or zucchini noodles for a low-carb meal.

Experiment with cheese varieties, such as Pepper Jack or cheddar, for a different flavor profile. And if you prefer to bake the meatballs, cook at 400°F (200°C) for 20-25 minutes before combining with the sauce and finishing under the broiler with cheese.

Nutrition Facts

Nutrient Amount per Serving (approx.)
Calories 320 kcal
Protein 22 g
Fat 24 g
Carbohydrates 6 g
Fiber 1 g
Sodium 680 mg

Note: Nutrition values are approximate and can vary depending on ingredient brands and portion sizes.

Serving Suggestions

Mississippi Meatballs are delightfully versatile when it comes to serving. Here are some ideas to complete your meal:

  • Serve over creamy mashed potatoes for a classic comfort food combo.
  • Pair with steamed white or brown rice to soak up the flavorful sauce.
  • Use as a hearty sandwich filling with some crusty rolls and extra cheese melted on top.
  • For a low-carb option, serve over sautéed spiralized zucchini or cauliflower rice.
  • Complement the richness with a fresh side salad like the Baby Spinach Salad Recipe Vegan: Fresh & Easy Ideas.

For a balanced meal, consider pairing the meatballs with green beans, roasted vegetables, or a simple coleslaw.

Conclusion

The Mississippi Meatball recipe is an excellent example of how simple ingredients can come together to create a dish that’s bursting with flavor and comfort. Its easy preparation and slow cooker method make it ideal for busy weeknights or entertaining guests without stress.

The combination of tender meatballs, creamy ranch seasoning, tangy pepperoncini, and melty cheese results in a dish that’s truly unforgettable.

Whether you’re a seasoned home cook or just starting out, this recipe is approachable and customizable to suit your tastes. Don’t hesitate to experiment with different cheeses, spices, or serving styles to make it your own.

For more delicious and easy recipes to complement your cooking journey, check out our guides on Afghan Vegetarian Pulao Recipe Easy and Delicious Guide, Vegan Recipes No Tofu: Delicious Plant-Based Meals, and Vegan Potato Corn Chowder Recipe for Cozy Comfort Food.

Give this recipe a try and enjoy a taste of southern comfort that’s sure to please everyone at your table!

📖 Recipe Card: Mississippi Meatball Recipe

Description: Tender beef meatballs simmered in a rich, buttery gravy with pepperoncini peppers and ranch seasoning. A flavorful and easy-to-make comfort dish perfect for any occasion.

Prep Time: PT15M
Cook Time: PT45M
Total Time: PT60M

Servings: 6 servings

Ingredients

  • 1 lb ground beef
  • 1 cup Italian breadcrumbs
  • 1/2 cup grated Parmesan cheese
  • 2 cloves garlic, minced
  • 1/4 cup chopped fresh parsley
  • 1 tsp salt
  • 1/2 tsp black pepper
  • 1 packet ranch seasoning mix (1 oz)
  • 1/2 cup unsalted butter (1 stick)
  • 4-5 pepperoncini peppers
  • 1/2 cup beef broth

Instructions

  1. Preheat oven to 350°F (175°C).
  2. In a bowl, mix ground beef, breadcrumbs, Parmesan, garlic, parsley, salt, and pepper.
  3. Form mixture into 18-20 meatballs and place in a baking dish.
  4. Place butter cubes evenly over meatballs.
  5. Sprinkle ranch seasoning over the meatballs and butter.
  6. Add pepperoncini peppers and pour beef broth around the meatballs.
  7. Bake uncovered for 35-40 minutes until meatballs are cooked through.
  8. Serve hot with sauce spooned over the top.

Nutrition: Calories: 350 kcal | Protein: 22 g | Fat: 27 g | Carbs: 8 g

{“@context”: “https://schema.org/”, “@type”: “Recipe”, “name”: “Mississippi Meatball Recipe”, “image”: [], “author”: {“@type”: “Organization”, “name”: “GluttonLv”}, “description”: “Tender beef meatballs simmered in a rich, buttery gravy with pepperoncini peppers and ranch seasoning. A flavorful and easy-to-make comfort dish perfect for any occasion.”, “prepTime”: “PT15M”, “cookTime”: “PT45M”, “totalTime”: “PT60M”, “recipeYield”: “6 servings”, “recipeIngredient”: [“1 lb ground beef”, “1 cup Italian breadcrumbs”, “1/2 cup grated Parmesan cheese”, “2 cloves garlic, minced”, “1/4 cup chopped fresh parsley”, “1 tsp salt”, “1/2 tsp black pepper”, “1 packet ranch seasoning mix (1 oz)”, “1/2 cup unsalted butter (1 stick)”, “4-5 pepperoncini peppers”, “1/2 cup beef broth”], “recipeInstructions”: [{“@type”: “HowToStep”, “text”: “Preheat oven to 350\u00b0F (175\u00b0C).”}, {“@type”: “HowToStep”, “text”: “In a bowl, mix ground beef, breadcrumbs, Parmesan, garlic, parsley, salt, and pepper.”}, {“@type”: “HowToStep”, “text”: “Form mixture into 18-20 meatballs and place in a baking dish.”}, {“@type”: “HowToStep”, “text”: “Place butter cubes evenly over meatballs.”}, {“@type”: “HowToStep”, “text”: “Sprinkle ranch seasoning over the meatballs and butter.”}, {“@type”: “HowToStep”, “text”: “Add pepperoncini peppers and pour beef broth around the meatballs.”}, {“@type”: “HowToStep”, “text”: “Bake uncovered for 35-40 minutes until meatballs are cooked through.”}, {“@type”: “HowToStep”, “text”: “Serve hot with sauce spooned over the top.”}], “nutrition”: {“calories”: “350 kcal”, “proteinContent”: “22 g”, “fatContent”: “27 g”, “carbohydrateContent”: “8 g”}}

Photo of author

Marta K

Leave a Comment

X